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1

From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma

Križaj, David, Ryskamp, Daniel A., Tian, Ning, Tezel, Gülgün, Mitchell, Claire H., Slepak, Vladlen Z., Shestopalov, Valery I.

Journal:

Current Eye Research

Year:

2014

Language:

english

File:

PDF, 990 KB

english, 2014

2

Gβ 5 Prevents the RGS7-Gα o Interaction through Binding to a Distinct Gγ -like Domain Found in RGS7 and Other RGS Proteins

Konstantin Levay, Jorge L. Cabrera, Daulet K. Satpaev and Vladlen Z. Slepak

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.16 MB

english, 1999

3

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

Almaça, Joana, Molina, Judith, Menegaz, Danusa, Pronin, Alexey N., Tamayo, Alejandro, Slepak, Vladlen, Berggren, Per-Olof, Caicedo, Alejandro

Journal:

Year:

2016

Language:

english

File:

PDF, 4.02 MB

english, 2016

4

Regulator of G protein signaling Gβ5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion

Wang, Qiang, Pronin, Alexey N., Levay, Konstantin, Almaca, Joana, Fornoni, Alessia, Caicedo, Alejandro, Slepak, Vladlen Z.

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

5

Identification of the Gβ5-RGS7 Protein Complex in the Retina

Jorge L. Cabrera, Fatima de Freitas, Daulet K. Satpaev, Vladlen Z. Slepak

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 975 KB

english, 1998

6

Involvement of endoplasmic reticulum stress in a novel Classic Galactosemia model

Tatiana I. Slepak, Manshu Tang, Vladlen Z. Slepak, Kent Lai

Journal:

Molecular Genetics and Metabolism

Year:

2007

Language:

english

File:

PDF, 522 KB

english, 2007

7

Diversity of Bacteria at Healthy Human Conjunctiva

Dong, Qunfeng, Brulc, Jennifer M., Iovieno, Alfonso, Bates, Brandon, Garoutte, Aaron, Miller, Darlene, Revanna, Kashi V., Gao, Xiang, Antonopoulos, Dionysios A., Slepak, Vladlen Z., Shestopalov, Valer

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 529 KB

english, 2011

8

The Presence of a Leu-Gly-Asn Repeat–Enriched Protein (LGN), a Putative Binding Partner of Transducin, in ROD Photoreceptors

Nair, K. Saidas, Mendez, Ana, Blumer, Joe B., Rosenzweig, Derek H., Slepak, Vladlen Z.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2005

Language:

english

File:

PDF, 520 KB

english, 2005

9

Application of surface plasmon resonance for analysis of protein–protein interactions in the G protein-mediated signal transduction pathway

Vladlen Z. Slepak

Journal:

Journal of Molecular Recognition

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

10

Autophosphorylation and ADP Regulate the Ca 2+ -Dependent Interaction of Recoverin with Rhodopsin Kinase †

Satpaev, Daulet K., Chen, Ching-Kang, Scotti, Anthony, Simon, Melvin I., Hurley, James B., Slepak, Vladlen Z.

Journal:

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

11

Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury

Dvoriantchikova, Galina, Ivanov, Dmitry, Barakat, David, Grinberg, Alexander, Wen, Rong, Slepak, Vladlen Z., Shestopalov, Valery I., Mattson, Mark P.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

12

Expression levels of RGS7 and RGS4 proteins determine the mode of regulation of the G protein-activated K+ channel and control regulation of RGS7 by Gβ5

Tal Keren-Raifman, Amal K. Bera, Dror Zveig, Sagit Peleg, D.Scott Witherow, Vladlen Z. Slepak, Nathan Dascal

Journal:

Year:

2001

Language:

english

File:

PDF, 474 KB

english, 2001

13

Signal-Dependent Translocation of Transducin, RGS9-1-Gβ5L Complex, and Arrestin to Detergent-Resistant Membrane Rafts in Photoreceptors

K.Saidas Nair, Nagaraj Balasubramanian, Vladlen Z. Slepak

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

14

Emerging roles of the single EF-hand Ca 2+ sensor tescalcin in the regulation of gene expression, cell growth and differentiation

Kolobynina, Ksenia G., Solovyova, Valeria V., Levay, Konstantin, Rizvanov, Albert A., Slepak, Vladlen Z.

Journal:

Journal of Cell Science

Year:

2016

Language:

english

File:

PDF, 474 KB

english, 2016

15

Up- or downregulation of tescalcin in HL-60 cells is associated with their differentiation to either granulocytic or macrophage-like lineage

Konstantin Levay, Vladlen Z. Slepak

Journal:

Experimental Cell Research

Year:

2010

Language:

english

File:

PDF, 728 KB

english, 2010

16

Helix 8 and the i3 Loop of the Muscarinic M3 Receptor Are Crucial Sites for Its Regulation by the Gβ5-RGS7 Complex

Karpinsky-Semper, Darla, Tayou, Junior, Levay, Konstantin, Schuchardt, Brett J., Bhat, Vikas, Volmar, Claude-Henry, Farooq, Amjad, Slepak, Vladlen Z.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.63 MB

english, 2015

17

Molecular Organization of the Complex between the Muscarinic M3 Receptor and the Regulator of G Protein Signaling, Gβ 5 −RGS7

Sandiford, Simone L., Wang, Qiang, Levay, Konstantin, Buchwald, Peter, Slepak, Vladlen Z.

Journal:

Year:

2010

Language:

english

File:

PDF, 4.88 MB

english, 2010

18

Teaching an old drug new tricks: agonism, antagonism and biased signaling of pilocarpine through M3 muscarinic acetylcholine receptor

Pronin, Alexey, Wang, Qiang, Slepak, Vladlen Z

Journal:

Molecular Pharmacology

Year:

2017

Language:

english

File:

PDF, 896 KB

english, 2017

19

Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury

Pronin, Alexey, Pham, Dien, An, Weijun, Dvoriantchikova, Galina, Reshetnikova, Galina, Qiao, Jianzhong, Kozhekbaeva, Zhanna, Reiser, Ashlyn E., Slepak, Vladlen Z., Shestopalov, Valery I.

Journal:

Frontiers in Molecular Neuroscience

Year:

2019

Language:

english

File:

PDF, 8.34 MB

english, 2019

20

Light-Mediated Activation of Rac-1 in Photoreceptor Outer Segments

Nagaraj Balasubramanian, Vladlen Z. Slepak

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 234 KB

english, 2003

21

Intramolecular Interaction between the DEP Domain of RGS7 and the Gβ 5 Subunit †

Narayanan, Vijaya, Sandiford, Simone L., Wang, Qiang, Keren-Raifman, Tal, Levay, Konstantin, Slepak, Vladlen Z.

Journal:

Year:

2007

Language:

english

File:

PDF, 468 KB

english, 2007

22

Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats

Oliver N. Hausmann, Wen-Hui Hu, Tal Keren-Raifman, D. Scott Witherow, Qiang Wang, Konstantin Levay, Beata Frydel, Vladlen Z. Slepak, John R. Bethea

Journal:

European Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 745 KB

english, 2002

23

Characterization of G-Protein |alpha Subunits in the GqClass: Expression in Murine Tissues and in Stromal and Hematopoietic Cell Lines

Thomas M. Wilkie, Peggy A. Scherle, Michael P. Strathmann, Vladlen Z. Slepak and Melvin I. Simon

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.25 MB

english, 1991

24

Characterization of Tescalcin, a Novel EF-Hand Protein with a Single Ca 2+ -Binding Site: Metal-Binding Properties, Localization in Tissues and Cells, and Effect on Calcineurin †

Gutierrez-Ford, Christina, Levay, Konstantin, Gomes, Aldrin V., Perera, Erasmo M., Som, Tapan, Kim, You-Me, Benovic, Jeffrey L., Berkovitz, Gary D., Slepak, Vladlen Z.

Journal:

Year:

2003

Language:

english

File:

PDF, 1.06 MB

english, 2003

25

Localization of the Sites for Ca 2+ -Binding Proteins on G Protein-Coupled Receptor Kinases †

Levay, Konstantin, Satpaev, Daulet K., Pronin, Alexey N., Benovic, Jeffrey L., Slepak, Vladlen Z.

Journal:

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

26

Molecular pathways of pannexin1-mediated neurotoxicity

Shestopalov, Valery I., Slepak, Vladlen Z.

Journal:

Frontiers in Physiology

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

27

Gα16, a G Protein α Subunit Specifically Expressed in Hematopoietic Cells

Thomas T. Amatruda III, David A. Steele, Vladlen Z. Slepak and Melvin I. Simon

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.09 MB

english, 1991

28

Mechanism of light-induced translocation of arrestin and transducin in photoreceptors: Interaction-restricted diffusion

Vladlen Z. Slepak, James B. Hurley

Journal:

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

29

[Progress in Molecular Biology and Translational Science] Molecular Biology of RGS Proteins Volume 86 || Chapter 6 Structure, Function, and Localization of Gβ5–RGS Complexes

Slepak, Vladlen Z.

Year:

2009

Language:

english

File:

PDF, 451 KB

english, 2009

30

Microbial life in the Lake Medee, the largest deep-sea salt-saturated formation

Yakimov, Michail M., La Cono, Violetta, Slepak, Vladlen Z., La Spada, Gina, Arcadi, Erika, Messina, Enzo, Borghini, Mireno, Monticelli, Luis S., Rojo, David, Barbas, Coral, Golyshina, Olga V., Ferrer,

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 971 KB

english, 2013

31

Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells

Evangelos Liapis, Simone Sandiford, Qiang Wang, Gabriel Gaidosh, Dario Motti, Konstantin Levay, Vladlen Z. Slepak

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

32

Interaction of retinal guanylate cyclase with the α subunit of transducin: potential role in transducin localization

Rosenzweig, Derek H., Saidas Nair, K., Levay, Konstantin, Peshenko, Igor V., Crabb, John W., Dizhoor, Alexander M., Slepak, Vladlen Z.

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 769 KB

english, 2009

33

Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury

Pronin, Alexey, Pham, Dien, An, Weijun, Dvoriantchikova, Galina, Reshetnikova, Galina, Qiao, Jianzhong, Kozhekbaeva, Zhanna, Reiser, Ashlyn E., Slepak, Vladlen Z., Shestopalov, Valery I.

Journal:

Frontiers in Molecular Neuroscience

Year:

2019

File:

PDF, 8.34 MB

2019

34

PhLPs and PhLOPs in the Phosducin Family of Gβγ Binding Proteins †

Craft, Cheryl M., Xu, Jun, Slepak, Vladlen Z., Zhan-Poe, Xinyi, Zhu, Xuemei, Brown, Bruce, Lolley, Richard N.

Journal:

Year:

1998

Language:

english

File:

PDF, 374 KB

english, 1998

35

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gα o and R7-binding Protein

Tayou, Junior, Wang, Qiang, Jang, Geeng-Fu, Pronin, Alexey N., Orlandi, Cesare, Martemyanov, Kirill A., Crabb, John W., Slepak, Vladlen Z.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 3.17 MB

english, 2016

36

Correction: Emerging roles of the single EF-hand Ca 2+ sensor tescalcin in the regulation of gene expression, cell growth and differentiation

Kolobynina, Ksenia G., Solovyova, Valeria V., Levay, Konstantin, Rizvanov, Albert A., Slepak, Vladlen Z.

Journal:

Journal of Cell Science

Year:

2017

Language:

english

File:

PDF, 94 KB

english, 2017

37

Evidence for Multiple Phototransduction Pathways in a Reef-Building Coral

Mason, Benjamin, Schmale, Michael, Gibbs, Patrick, Miller, Margaret W., Wang, Qiang, Levay, Konstantin, Shestopalov, Valery, Slepak, Vladlen Z., Mozumdar, Subho

Journal:

Year:

2012

Language:

english

File:

PDF, 6.25 MB

english, 2012

38

Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

Susan M. Hanson, Whitney M. Cleghorn, Derek J. Francis, Sergey A. Vishnivetskiy, Dayanidhi Raman, Xiufeng Song, K. Saidas Nair, Vladlen Z. Slepak, Candice S. Klug, Vsevolod V. Gurevich

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

39

Phosphorylation of the Regulator of G Protein Signaling RGS9-1 by Protein Kinase A Is a Potential Mechanism of Light- and Ca 2+ -Mediated Regulation of G Protein Function in Photoreceptors †

Balasubramanian, Nagaraj, Levay, Konstantin, Keren-Raifman, Tal, Faurobert, Eva, Slepak, Vladlen Z.

Journal:

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

40

The Gβ 5 −RGS7 Complex Selectively Inhibits Muscarinic M3 Receptor Signaling via the Interaction between the Third Intracellular Loop of the Receptor and the DEP Domain of RGS7 †

Sandiford, Simone L., Slepak, Vladlen Z.

Journal:

Year:

2009

Language:

english

File:

PDF, 820 KB

english, 2009

41

Elemental sulfur and acetate can support life of a novel strictly anaerobic haloarchaeon

Sorokin, Dimitry Y, Kublanov, Ilya V, Gavrilov, Sergei N, Rojo, David, Roman, Pawel, Golyshin, Peter N, Slepak, Vladlen Z, Smedile, Francesco, Ferrer, Manuel, Messina, Enzo, La Cono, Violetta, Yakimov

Journal:

The ISME Journal

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

42

Direct Binding of Visual Arrestin to Microtubules Determines the Differential Subcellular Localization of Its Splice Variants in Rod Photoreceptors

Nair, K. Saidas, Hanson, Susan M., Kennedy, Matthew J., Hurley, James B., Gurevich, Vsevolod V., Slepak, Vladlen Z.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 800 KB

english, 2004

43

Functional Analysis of a Dominant Negative Mutant of Gα i2

Slepak, Vladlen Z., Katz, Arieh, Simon, Melvin I.

Journal:

Journal of Biological Chemistry

Year:

1995

File:

PDF, 2.53 MB

1995

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